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- alt.drugs Clandestine Chemistry Primer & FAQ
- (Frequently Asked Questions)
-
- Version: 2.7
- (c) 1995 Yogi Shan
- <yshan@bnr.ca>
-
- "Give me an underground laboratory,
- half a dozen atom-smashers, and a
- beautiful girl in a diaphanous veil
- waiting to be turned into a chimpanzee,
- and I care not who writes the nation's
- laws."
- -- S.J. Perelman
-
- ------------------------------
-
- Subject: 1. Introduction and Miscellanea
-
- Introduction
- ------------
-
- It was the best of times. It was the worst of times.
-
- UseNet is one of the most amazing phenomenon I have ever seen: a
- dynamic synthesis of human knowledge, thought, and understanding.
- Where else but on the 'Net could I post a comment about an obscure
- line from the SF cult movie "Blade Runner" in the evening, and
- find half a dozen follow-up posts from fellow aficionados scattered
- across the globe, by the next day?
-
- But as the human spirit soars to unimaginable heights, so does it
- wallow in the gutter of depravity with equal, if not greater joy.
-
- As a high traffic newsgroup, alt.drugs generates about 130 posts a
- day. And according to news.lists estimates (Jan. 1995), has 120,000
- daily readers, a possibly conservative figure.
-
- A topic of continuing interest -- enough to result in the 1994
- spawning of its own subgroup, alt.drugs.chemistry -- is the subject
- of "underground" or "clandestine" chemistry: the covert manufacture
- of illicit drugs.
-
- In an undoubtedly vain attempt to stem the flow of wasted bandwidth
- arising from idiotic "How do you make <illegal_drug>?" questions on
- the alt.drugs* and sci.chem newsgroups, I have assembled this FAQ/
- Primer.
-
- Copyright Notice
- ----------------
-
- This document is Copyright (c) 1995 by Yogi Shan. This text, in
- whole or in part, may not be sold in any medium, including but not
- limited to electronic, CD-ROM, or print, without the express written
- permission of Yogi Shan.
-
- Permission is granted to reproduce for individual, personal, non-
- commercial use, in electronic form *ONLY*, provided that no part
- of this document is modified in any way, including this notice.
-
- I reserve the right to revoke this permission at any time (though
- I don't presently anticipate doing so).
-
- Any commercial, organizational, institutional, or governmental use
- is expressly forbidden without prior written permission.
-
- REWARD OFFERED!: If you know of any violation of this copyright
- notice, please show your gratitude to the author for making
- available this document, by letting him know. As well, I'll give
- you 25% of any damage award (net) I get from legal action.
-
- If you have found this document of use, a $5 donation is requested
- to any of the following: the American Civil Liberties Union (ACLU),
- Amnesty International, or any schizophrenia/mental health charitable
- organization. Please let the author <yshan@bnr.ca> know if you have
- made such a donation. It will truly brighten his day. Thanks!
-
- Where To Find This Document
- ---------------------------
-
- <http://hyperreal.com/drugs/faqs/FAQ-Clandestine-Chemistry>
- <ftp://www.damicon.fi/pub/mirrors/hyperreal.com/drugs/faqs/
- FAQ-Clandestine-Chemistry>
-
- Revision History
- ----------------
-
- Initial Draft...............................v. 1.0 950319
-
- Major Revision............................. v. 2.0 950419
-
- Added Synthetic Heroin and Amphetamine
- Impurities Sections.........................v. 2.5 950518
-
-
- Acknowledgements
- ----------------
-
- Thanks to Malcolm, Lamont, Pearl, KMH, and especially Denni,
- for their comments and input.
-
- Disclaimer
- ----------
-
- Nothing in this document should [obviously] be construed as
- advocating or promoting the criminal violation of any laws.
-
- Neither does the author take responsibility should you poison,
- injure, or blow yourself or others to smithereens doing
- something alluded to in this document.
-
- ------------------------------
-
- Subject: 2. Table of Contents
-
- 1. Introduction and Miscellanea
-
- 2. Table of Contents
-
- 3. Net.resources
-
- alt.drugs
- alt.drugs.chemistry
- sci.chem
- misc.legal & misc.legal.moderated
- Anon Remailers
-
- 4. Books: The Good, The Bad, And the Ugly
-
- Psychedelic Chemistry
- PIHKAL: A Chemical Love Story
- Marijuana Chemistry
- The Anarchist Cookbook
- Other Books
- Popular Culture
-
- 5. So You Want to Make <Illegal_Drug>
-
- The Merck Index
- Chemical Abstracts
-
- 6. Historical References on Underground Chemistry
-
- "No One Expects the Spanish Inquisition!"
- Speed Labs
- LSD Manufacturing: Boys -- and Girls -- in the 'Hood
- A Selected Bibliography on Synthetic Heroin
-
- 7. "You Have Greatly Misunderstood the Purpose of the Net"
-
- Trade Secrets
- Killing the Goose that Laid the Golden Egg
- "Please e-mail me the answer to my [Stupid] Question."
- "Why Didn't Anyone Answer my [Stupid] Question?"
- Is the DEA on the Net?
- Can I Rely on Net.answers to my Questions?
-
- 8. The Law: Do Not Pass Go, Do Not Collect $200,000
-
- 9. Morality & Ethics
-
- ------------------------------
-
- Subject: 3. Net.resources
-
- "It's propping up the governments,
- In Colombia an' Peru,
- You ask any DEA man,
- He'll say, 'There's nothin' we can do.'
- From the Office of the President,
- Right down to me an' you.
- Me & you."
-
- -- "Smuggler's Blues"
- Glenn Frey/Jack Tempchin (1984)
-
- alt.drugs
- ---------
-
- A document listing a plethora of net.resources may be found at:
-
- <http://hyperreal.com/drugs/faqs/resources.html>
- <ftp://hyperreal.com/drugs/00-MORE.FILES>
-
- Other World Wide Web and other Net sites are:
-
- <http://www.lycaeum.org/> [an "entheogen" group]
- <http://www.paranoia.com/drugs/>
- <gopher://hemp.uwec.edu/>
- <http://www.sonic.net/~raptor/trakman/index.html>
- <http://www.csp.org/entheogen.html> [another "entheogen" group]
- <http://www.undcp.org/> [U.N. Drug Control Program]
- <http://www.usdoj.gov/dea/pubs/pblist.htm> [the U.S. DEA]
- <http://www.crl.com/~zbear/> [Owsley Stanley's artwork]
-
- There are a variety of FAQs and other documents, which range from
- excellent to not-so-excellent, available at the hyperreal.com site
- (the "official" alt.drugs site). In case it changes (making this
- reference stale), the pointer to the site is regularly posted to
- alt.drugs as the alt.drugs FAQ and the Net Resources FAQ.
-
- The "Australian Natural Highs FAQ" and "Chemical Extraction FAQ" are
- particularly note-worthy, since extraction of botanical drugs is the
- procedure most likely to be successful for the amateur. The chemical
- synthesis section of "PIHKAL" (infra) may also be found at
- hyperreal.com.
-
- The book "E for Ecstasy" (1993), by the Englishman, Nicholas Saunders
- <Nicholas@neals.cityscape.co.uk> is also available at hyperreal.com
- as well as at:
-
- <http://www.cityscape.co.uk/users/bt22/>
-
- There's an interesting piece in the Notes section (at the end),
- describing the trials and tribulations of clandestine MDMA
- manufacture as experienced by some English entrepreneurs. The
- appendix (by Alexander Shulgin) lists a number of synthetic
- references for MDMA, though it is incomplete. The MDMA
- FAQ at hyperreal.com has a good chemistry section too.
-
- Email <Cora.Belgique@agora.stm.it> for a regular e-mail report
- summarizing an extensive variety of newspaper reports on issues
- of drugs and drug control. Focus is on European newspapers by
- the anti-prohibition group. Not really clandestine chemistry
- related, but interesting nonetheless.
-
- As well, some very high quality chemical and pharmacological
- information is occasionally posted by some readers of alt.drugs.
- However, the signal-to-noise ratio is very low (< 1:100), so you
- have to pay close attention. Even worse are the idiots who have
- read a book or two and now fancy themselves as experts. They are
- not.
-
- As with the rest of the net, reputation is a good *indication*.
- Majority rules is not. Never gamble where issues concern health,
- safety, or freedom. In the interests of eugenics, feel free to
- ignore the previous statement.
-
- Though the focus is on "smart" drugs, alt.psychoactives is a related
- group with a much lower traffic level that you might want to check
- out/post to. Ditto for alt.drugs.psychedelic.
-
- alt.drugs.chemistry
- -------------------
-
- Make it easy for the DEA: post your chemistry questions here. After
- all, we wouldn't want them having to wade through a lot of silly "I'm
- really baked! (Hi, Mom!)" posts.
-
- Less well propagated on the net (by half!) than alt.drugs, for obvious
- reasons. In order to maximize your audience, cross-post to alt.drugs
- if you're going to post here.
-
- sci.chem
- --------
-
- Many a great mind will attempt to tap into the knowledge-base of
- *real* chemists in their glorious quest for riches, er, I mean
- enlightenment, by posting thinly disguised drug manufacturing
- questions to sci.chem. Usually related to the manufacture of
- methamphetamine, these queries generally fool only the totally
- naive.
-
- The questions are generally phrased around the topic of reducing
- agents, reduction of benzylic alcohols, reductive amination, or
- the ever-popular benzyl methyl ketone/phenylacetone, the archaic
- pre-IUPAC names for P-2-P, the notorious (and scheduled) amphetamine
- precursor. (P-2-P was mentioned briefly in the Harrison Ford movie
- "Witness".)
-
- Such questions seldom produce the desired result, though I suppose
- there's no harm in trying, as long as you don't mind being flamed,
- or having your name passed to the relevant civil authorities. On
- the other hand, I've also seen some craftily worded drug synthesis
- questions successfully run the gauntlet without detection.
-
- Posting anonymously tips off many people to the true nature of your
- (nefarious) motives, by the way.
-
- misc.legal & misc.legal.moderated
- ---------------------------------
-
- Get all your legal questions answered NOW. There's no Newsfeed in
- Leavenworth.
-
- Anon Remailers
- --------------
-
- Anon.penet.fi is no longer available, but the many U.S. cypherpunks
- anon remailers are even better, and PGP (Pretty Good Privacy), for
- encrypting e-mail, should be _de rigueur_.
-
- The fact that these utilities are easily available (check out
- alt.security.pgp, alt.privacy.anon-server, alt.anonymous, and
- sci.crypt; or wait for the two different PGP FAQs to appear in
- news.answers or alt.answers; ask around if you need help!), but
- not widely used, is _de facto_ evidence that drug use impairs good
- judgement, if not the mental faculties, in general.
-
- For a current list of various anonymous remailers:
-
- <http://www.cs.berkeley.edu/~raph/remailer-list.html>
-
- or alternatively: finger <remailer-list@kiwi.cs.berkeley.edu>
-
- ------------------------------
-
- Subject: 4. Books: The Good, The Bad, And The Ugly
-
- "[It's] the last American folk adventure...
- the light in the moon...narcotics agents
- chasing you all over the land. It's a
- fantasy made real."
-
- -- George Marquardt, convicted
- drug chemist, on his profession
-
- As with the Net in general, there is a paucity of accurate
- information available on the subject of illicit drugs. Even
- the fact of publication is not necessarily a guarantee of any
- sort of technical legitimacy, particularly, though not limited
- to, "counter-culture" efforts.
-
- There are many reasons why people write books, but making money
- is one of the biggest. When the subject is of an illegal nature,
- the likelihood of inadequate, incomplete, or blatantly wrong
- information is even higher than usual.
-
- Companies like Paladin, Delta Press, and Loompanics are typical
- purveyors of such trashy misinformation under cover of the U.S.
- First Amendment.
-
- Ever seen the list of "underground" books by Ragnar Benson &
- Duncan Long? How many things can these guys be "expert" in?
- Not bloody likely. What's that maxim? If you can't do, teach.
-
- One of the more egregious examples of gross error in the drug
- book realm, was the "Cocaine Consumer's Handbook" by one David
- Lee (Berkeley, California: And/Or Press, 1976). In it, Mr.
- Lee flogged the notorious "Clorox [bleach] Test" for cocaine.
- This test, described in excruciating detail, and complete with
- color photographs, purported to detect not only eight different
- adulterants and diluents, but the relative percentage purity of
- the cocaine itself.
-
- Alas, several years later, the test was finally unmasked as utter
- nonsense by PharmChem, a reputable Menlo Park, CA street drug
- analysis organization. Their testing established that the orange
- color produced when lidocaine is present in the sample being tested
- was the extent of the Clorox Test's scope and usefulness.
-
- Undeterred, Mr. Lee -- shameless scallywag and possible shill for
- the Clorox Company -- came out in 1981 with a brand new book, "The
- Cocaine Handbook: An Essential [sic] Reference." Alluding coyly to
- the PharmChem "controversy", Lee continued to include the Clorox
- Test (now illustrated with black & white photos), but added an
- equally useless "foil burn" test (with color pics), along with the
- detailed procedure for home manufacture of freebase ("crack") cocaine.
-
- Cocaine use had by now begun to lose its cachet, as well as more than
- the occasional user, so the ever-helpful Lee covered his bases and
- assuaged his seemingly bullet-proof conscience by including a thirteen
- page (!) list of addiction service agencies.
-
- So it goes.
-
- There are many other such errors large and small that have made it
- into print. Books like the "Anarchist Cookbook" (infra) are ridden
- with them. For instance grafting a hop plant onto a marijuana root
- (debunked by Crombie & Crombie (1975) and Starks (1990), infra),
- and making meth from soft coal, ammonia, and bluing compound
- (described in "Complete Guide to the Street Drug Game" by Scott
- French. Secaucus, NJ: Lyle Stuart (1976)) are all complete bunk.
-
- Militating against the writing of quality books is that the fact of
- the matter is that if you gain enough knowledge to be a competent
- underground chemist, you can snag good paying employment -- and not
- risk your freedom and mortal soul through involvement with the drug
- trade.
-
- (Then again, there's the infamous case of Michael Hovey,
- the young DuPont chemist gone feral ["Chem. & Eng. News",
- 851223 & 860310].
-
- Working at DuPont's Delaware research facility in quiet
- desperation, and apparently inspired by lurid media
- accounts of Fentanyl analogue manufacture, out of the
- blue he decided to go into the synthetic heroin
- business.
-
- Unfortunately for him, he had no contacts for distributing
- his 3-methylfentanyl product. In a hopelessly amateurish
- attempt to make such contacts -- he approached a black
- DuPont janitor -- he was promptly turned in, arrested,
- convicted, and sentenced to an 18 year Federal prison term
- (Ouch!). For apostasy, more than anything else.
-
- Needless to say, Dr. Hovey was also promptly fired.
-
- Cf. "New Scientist", 930807, p. 21-22, for a different
- case at Parke-Davis Pharmaceuticals in England.)
-
- Nonetheless, reliable books on clandestine chemistry have been
- published. Below are some of the more accurate efforts I have seen.
-
- It is no coincidence that the "good" ones originate from the San
- Francisco Bay area, a center of politically-motivated underground
- chemistry since the early Sixties.
-
- These books may be "illegal" and/or subject to confiscation by
- postal/customs authorities in countries such as Canada and Australia.
-
- "Psychedelic Chemistry"
- ----------------------
-
- M.V.Smith. Port Townsend, Washington: Loompanics (1981).
- <loompanx@olympus.net> (P.O. Box 1197, Port Townsend, WA 98368).
-
- Largely abstracted from the specialist literature, PC is the
- hands-down leader in a very small field. It's a classic. LSD,
- mescaline, psychedelic amphetamines, and THC are thoroughly
- covered, among others. One of the more interesting "recipes"
- is an actual underground one for the large-scale production of
- LSD; to wit, a two million (!) dose batch.
-
- M.V. Smith (a reference to the Martian messiah in Robert Heinlein's
- '60s SF classic, "Stranger in a Strange Land") is a pseudonym for
- Michael Starks, author of "Marijuana Chemistry" (infra). PC was
- originally published by San Francisco's RipOff Press, and --
- unfortunately for the budding felon -- requires a thorough grounding
- in organic chemistry to make heads or tails of. Though out of date,
- it is generally accurate.
-
- There are two known serious mistakes. The first is an MDA synthesis
- where hydrogen peroxide is substituted for water, with possibly
- unfortunate results. This mistake was copied from the "Chemical
- Abstracts" (infra) abstract that was the source of this entry.
-
- The second error is the extension of the Ritter Reaction to MDA.
- According to a 1958 _Bull. Soc. Chim. Fr._ paper and others,
- apparently ring-substituted allylbenzenes will cyclicize to the
- 3,4-dihydro-isoquinoline.
-
- Loompanics also sells a few other books on clandestine chemistry,
- which range from trash to OK. An example is Jim DeKorne's
- "Psychedelic Shamanism", which is in the worthless trash category.
-
- DeKorne is apparently a devotee of botanical psychedelics --
- though not devoted enough to bother accurately documenting chemical
- extraction procedures. [See the hyperreal.com web site for two
- reviews of DeKorne's book, as well as the two previously mentioned
- alt.drugs FAQs which are not only better, but free to boot.]
-
- "PIHKAL: A Chemical Love Story"
- ------------------------------
-
- ("Phenethylamines I Have Known And Loved"), Alexander & Ann
- Shulgin. Berkeley, California: Transform Press (1991).
- (P.O. Box 13675, Berkeley, CA 94701).
-
- Authored by a published, legitimate, and respected chemist (his
- non-chemist wife is co-author), PIHKAL thoroughly outlines the
- synthesis of a couple of hundred psychedelic amphetamines (N,a-
- alkylarylethylamines and congeners), including MDMA.
-
- Many of these compounds, such as STP, were first synthesized,
- and/or pharmacologically noticed, by Shulgin himself, beginning
- in the mid-60s while working for Dow Chemical (Smith & Luce,
- infra). _PIHKAL_ was Shulgin's "going public" with the fact
- that his work continued long after government funding was shut
- off, Schedule I classification, and finally, the Analogue Act,
- had strangled the field this Ghost in the Machine advocated.
-
- PIHKAL is an expanded and metamorphosed version of a lengthy
- chapter by Shulgin in the "Handbook of Psychopharmacology" (11:
- 243-333 (1978)).
-
- Like PC, you have to be a chemist to understand the syntheses,
- since explanations of the synthetic routes are either sparse
- or non-existent. The "recipe" section is available at the
- hyperreal.com site.
-
- It is believed that Dr. Shulgin is less respected -- in more staid
- circles -- since publication of his _magnum opus_.
-
- In 1995, the U.S. DEA, in likely retribution, and displaying their
- trademark sense of humor, raided his Lafayette, California lab,
- stripped him of his license to handle Schedule I Controlled
- Substances, and fined him $25,000.
-
- "Marijuana Chemistry"
- --------------------
-
- Michael Starks. Berkeley, California: Ronin Press (1990).
- (P.O. Box 1035, Berkeley, CA 94701).
-
- A detailed examination, written for the layman, of the world's most
- thoroughly persecuted peasant inebriant. Extensively covers potency
- issues in growing, home hash oil manufacture, and isomerization.
-
- Good discussion on the pros and cons of various extraction solvents.
- Contains an updated section on THC synthesis from PC, which Starks
- also wrote. Originally published as "Marijuana Potency" (And/Or
- Press, 1977).
-
- "The Anarchist Cookbook"
- -----------------------
-
- William Powell. Secaucus, NJ: Barricade Books (1971)
- ($22 [includes S&H] from P.O.Box 1401, Secaucus, N.J. 07096).
-
- I mention the infamous AC because of its notoriety, popular appeal
- (over a million copies in circulation), and simply because it was
- the first.
-
- A veritable grab-bag of techniques for psychedelic urban guerrilla
- warfare, the AC contains recipe-style, how-to sections on the home
- manufacture of drugs and explosives, demolitions, weapons, and
- electronic eavesdropping, making the AC the first mass market
- publication created with the express purpose of subverting modern
- technology in order to overthrow the government.
-
- For this reason alone, the book is a classic.
-
- Unfortunately, the book is outdated and full of all sorts of mistakes,
- though most of the dangerous ones are confined to the explosives
- chapter. The DMT recipe will *not* work (you have to use anhydrous
- dimethylamine, not the 40% aqueous commercial solution that the AC
- implies), for instance, Aldrich won't sell you trimethoxyphenylaceto-
- nitrile, and the "bananadine" and peanut skin recipes are nonsense.
-
- Thus, I cannot recommend the AC except as a curiosity, a stepping
- stone to more serious works, or to impress cheap dates with your hipness.
-
- But then again, with its healthy dollop of revolutionary leftist
- ideology, I think that the AC was never meant to be so much an end
- in itself, but more a beginning.
-
- Other Books
- -----------
-
- "Cannabis Alchemy" (by D. Gold), "Dr. Atomic's Marijuana Multiplier"
- (a comic by Larry Todd), "Basic Drug Manufacture", and "The Book of
- Acid" (by Adam Gottlieb) are several old, but reasonably accurate
- reprint pamphlets.
-
- Though technically accurate, they sprang forth from a time when
- chemical sales were much less strictly controlled. Use at face
- value is pretty much guaranteed to end you up in jail, rank
- amateur status notwithstanding.
-
- They are available from a number of '60s reprise, counter-culture
- suppliers (such as FS Book Co., P.O. Box 417457, Sacramento, CA
- 95841) that advertise in such drug publications as the mass-market
- "High Times" <http://www.hightimes.com/~hightimes/welcome.html>
- and the smaller, shoestring-budget "Psychedelic Illuminations"
- <http://www.lycaeum.org/~jkent/pi/> or (P.O. Box 3186, Fullerton,
- California 92634).
-
- There are other books available from Loompanics that I have seen
- mentioned in alt.drugs, however I off-loaded my rakish friends many
- years ago, and so haven't had the opportunity to borrow and review
- them (donations cheerfully accepted!).
-
- These include "Recreational Drugs" (by Prof. Buzz), "Secrets of
- Methamphetamine Manufacture" (4th ed., Uncle Fester), and "The
- Construction and Operation of Clandestine Drug Laboratories" (Jack
- B. Nimble). No word on whether a "Get Out of Jail Free" Card
- comes with purchase. The imaginative pseudonyms may give you some
- clue as to the quality of these books, which is quite uneven.
-
- Fester seems to focus on the Leuckart reaction, which though simple
- to do, has a rather low yield. It's obvious he was clever enough to
- locate the "Org. Synth. Collective Volumes", though this is not
- particularly clever, in my mind. He repeats the Ritter reaction
- error mentioned previously.
-
- Fester has also written "Practical LSD Manufacture" which is an
- interesting title given that unlike his amphetamine book, it
- seems highly doubtful that he has any actual practical experience
- in this area. His horn-tooting about having discovered the
- infamous "Operation Julie" LSD formula (Lee & Shlain, infra,
- p. 288) is utter nonsense: propionyl anhydride is a reportable
- precursor due to its utility in reversed ester synthetic opiate
- production.
-
- Popular Culture
- ---------------
-
- The underground chemist as pop icon. The incorporation of the
- clandestine chemist into popular culture has been limited with
- the unfamiliarity of the public -- and indeed the authors and
- screen-writers that entertain them -- with the highly technical
- nature of their work.
-
- With _shlock_ and mediocrity the norm, verisimilitude has certainly
- always been a rather rare commodity on the big screen, but
- particularly so in the case where technocriminal activity is
- portrayed.
-
- On the other hand, notable high-points in this genre are worth
- mentioning, since some of the scenes are quite memorable
- technically, with their own cult following amongst those in
- the know.
-
- They include "Three Days of the Condor" (1975) with Robert Redford
- and Faye Dunaway (phone phreak/wireman/assassin); "Thief" (ca. 1980)
- with James Caan as the safecracker with the thermal lance; and "To
- Live & Die in L.A." (1985) directed by William Friedkin, and starring
- Willem Dafoe as the deviant master counterfeiter (the legal info is
- inaccurate, the offset photolithography is bang on.).
-
- The first portrayal of an underground chemist in the mass media
- that I've seen, was in the 1971 Academy Award winning movie, "The
- French Connection" (also directed by Friedkin), a fictionalized
- account of an actual N.Y. City Police investigation that is more
- popularly remembered for its excellent car chase scene.
-
- Pat McDermott plays Howard the junkie chemist, making two brief
- appearances to test, for New York gangsters, the 60 kg. heroin
- shipment from Marseilles that is the subject of the film.
-
- In the first test, the chemist performs a "Thiele tube melting point
- test" to determine the purity of the heroin. An archaic, low-tech,
- but quite effective testing method for relatively pure organics,
- this test utilizes the fact that 100% pure heroin hydrochloride (aka
- "China White") melts at precisely 243-244 deg. C.
-
- The more "cut" (diluted) or impure the heroin, the wider the temper-
- ature range from initial to complete melting, and the lower the
- initial temperature of the melting range.
-
- In the scene, Howard fills the Thiele tube with mineral oil, places
- a tiny sample of the heroin to be tested into a capillary tube
- sealed at one end, and immerses it, tied to a thermometer, into the
- oil bath.
-
- The oil bath temperature is then slowly raised by heating with an old-
- style chemistry set alcohol burner as the chemist watches for the
- crystalline sample to begin melting, while he simultaneously monitors
- the temperature.
-
- His running commentary on the heroin's purity begins at an arbitrary
- baseline ("blast off") of 180 degrees Centigrade:
-
- "Blast off! ...One-eight-oh...
- Two Hundred: Good Housekeeping Seal of Approval...
- Two-ten: U.S. Government Certified...
- Two-twenty: Lunar trajectory; Junk-of-the-Month Club sirloin
- steak...
- Two-thirty: Grade A poison...
-
- "Absolutely dynamite. [It's] 89% pure 'junk' -- best I've
- ever seen. If the rest is like this, you'll be dealin' on
- this load for two years."
-
- In Howard's second appearance, he performs the crude but quick
- Marquis Reagent spot test as a final, last minute check before the
- smack shipment and buy money change hands. The Marquis Reagent, a
- formaldehyde/sulfuric acid mixture, turns purple on contact with
- opiates. [In at least some home-video versions of the movie this is
- not clear, and the purple color looks orange.]
-
- A sleazy, underwear-less biker "cook", replete with triple-necked,
- ground-glass jointed flask, is portrayed as a minor character in the
- 1991 movie, "Rush". He's the one that coerces the female undercover
- narc [Jennifer Jason Leigh] into dropping some sort of psychedelic
- following a drug buy. (The reason he French kissed her at the end of
- this scene, by the way, is to make sure that she had really swallowed
- the pill. She had -- rather than holding it under her tongue like
- most narcs would -- which no doubt saved her from some immediate
- grief.)
-
- "Beyond the Law" (1993, released in Europe as "Fixing the Shadow")
- stars Charlie Sheen in this somewhat cheezy "true story" of a narc
- infiltrating some bikers running a speed lab.
-
- In the fiction book category, "The Alchemist" by Kenneth Goddard
- (N.Y.: Bantam, 1985), is a cliche-ridden potboiler about a manufac-
- turer of PCP analogues. Gives the whole business a bad name [the
- fiction book business, that is].
-
- A nice color poster showing a submachine-gun-totting, ninja-ed out
- raiding party member sporting a "DEA Clandestine Laboratory Enforcement
- Team" patch is available from Delta Press <deltagrp@eldonet.com> for
- $11.95 + 3.75 S&H.
-
- ------------------------------
-
- Subject: 5. So You Want to Make <Illegal_Drug>
-
- "And then there came the night of the greatest ever raid,
- They arrested every drug that had ever been made,
- They took 82 laws,
- Through 82 doors,
- And they didn't halt the pull,
- Till the cells were all full,
- Cuz Julie's workin' for the Drug Squad,
- Julie's been workin' for the Drug Squad."
-
- -- "Julie's in the Drug Squad"
- The Clash (1978)
-
- The "Merck Index"
- ----------------
-
- I can answer 90% of the technical questions posted to alt.drugs
- by merely leafing through the copy I have at home of this exceedingly
- useful book. It's truly the chemist's bible. The Merck is a
- dictionary of thousands of chemicals, listing their structure, basic
- chemical and pharmacological properties (though the angle seems to
- be more along the lines of a medicinal chemist), and pointers to
- synthesis and more detailed info.
-
- "The Merck" -- as it's referred to by those in the know -- will be in
- the reference section of any university science library, and any decent
- public library. No, it isn't available on the Net.
-
- The Merck -- not to be confused with the "Merck Manual" -- is a window
- to the scientific specialist literature. Expect to have to learn some
- chemistry to use it effectively. Your librarian can help you on
- locating the journals referenced. (Don't worry, I doubt she'll have
- the slightest clue what you're up to.) Most of the articles you seek
- will be well-thumbed. Some will have been razored out of their volume:
- living testimony to the "thermoplastic" morals of many a drug user,
- unaware that desecrating books is the mark of low-born barbarians,
- and a sin against God and Man.
-
- "Chemical Abstracts"
- -------------------
-
- Most of the syntheses referenced in the Merck will be in old, obscure,
- and sometimes difficult to obtain journals, even if you do live near
- a university.
-
- [Side Note: A number of people may have been needlessly
- harmed by a poorly made batch of the synthetic opiate,
- MPPP, because a paper on a previous instance of this
- happening was rejected by the mainstream medical journals
- (it was finally published in a new and obscure journal,
- "Psychiatry Research", where it languished unnoticed).]
-
- Have no fear, Chem. Abs. is here!
-
- Though the actual paper is *always* best, abstracts of U.S. and
- foreign chemical patents and journal articles can also be found
- in this invaluable journal. Any chem student, or the reference
- librarian, can show you how to use it. You'll have to learn even
- more chemistry to effectively use Chem. Abs. (Hint: Me = methyl,
- Ac = acetyl).
-
- Chem.Abs. is also good if you only read English, providing a
- convenient translation of foreign language papers. (Personally,
- I have found that being able to translate German -- as well as
- the occasional French and Italian paper -- extremely useful in
- my forays into the literature).
-
- ------------------------------
-
- Subject: 6. Historical References on Underground Chemistry
-
- "I had a number of projects that I wished to pursue
- in France. I wanted to learn to speak the language,
- I wanted to break my father loose from his grief
- over the death of my mother, and especially, I
- wanted to put a methylenedioxy group in place of
- two of the methoxy groups in Trimethoxyamphetamine."
-
- -- Dr. Alexander Shulgin
- "PIHKAL"
-
- Ah yes. History, "the lie that all historians can agree on."
-
- There is a dearth of historical information available on the subject of
- underground/clandestine chemistry. Considering the shadowy and covert
- nature of the business, this is really not surprising.
-
- If I've missed any noteworthy publications, please let me know.
-
- I could also have written sections on MDMA, Quaaludes, PCP/Angel Dust,
- and heroin (both natural and synthetic analogues), but for reasons of
- brevity, I won't (except for a selected bibliography on synthetic
- opiates). Interestingly, different drugs have radically different
- stories reflecting their unique origins, histories, markets, and
- pharmacology.
-
- Going back a few decades, the moonshining business in the rural
- Eastern U.S. provides an interesting historical antecedent to the
- modern day drug manufacturing business. Serious researchers are
- advised to examine this angle.
-
- I found the parallels quite fascinating, from the analogous precursor
- controls on sugar, to the flurry of Federal laws passed. (Ever wonder
- why U.S. liquor bottles are embossed with the warning "Federal Law
- prohibits re-filling"?)
-
- "No One Expects the Spanish Inquisition!"
- ----------------------------------------
-
- "A little poison now and then, that makes for
- agreeable dreams. And much poison in the end,
- for an agreeable death."
-
- -- "Thus Spake Zarathustra"
- Friedrich Nietzsche
-
- Probably the best layman's overview of the chemistry of illicit
- drugs may be found in the ground-breaking paper, "The Clandestine
- Drug Laboratory Situation in the U.S.", J.For.Sci., 28(1):18-31
- (1983) by Richard S. Frank, then Chief of the DEA's Forensic
- Science Division.
-
- Complete with chemical diagrams, and covering the detailed synthetic
- routes to methamphetamine, amphetamine, P-2-P, MDA, PCP, and metha-
- qualone (quaaludes), the actual literature citations are conspic-
- uously absent, no doubt to prevent amateurs from using the article
- as a cookbook.
-
- Nonetheless, publication of such a complete blueprint represented
- a significant shift in strategy for the DEA's Forensic Division,
- which apparently decided that underground laboratory activity had
- become so widespread (it had: see next section) that the
- advantages of dissemination in the open literature -- education
- of state, local, and international forensic scientists and
- investigators -- outweighed the disadvantages.
-
- However, at the same time, it is also interesting to note that
- this article deliberately provided clandestine chemists with a
- correction to a wrong procedure. An obscure method for producing
- methamphetamine involves the condensation of the Grignard, benzyl
- magnesium chloride, with other reactants. However the order of
- mixing of these reagents in one of the reaction's original literature
- cites (a Chem. Abs. abstract of a British Patent) is incorrect.
- This error was then reproduced in a shoddy underground drug-making
- guide.
-
- Unfortunately, even incorrectly mixed, instead of the reaction
- simply failing, a white, crystalline -- and toxic -- solid
- will still be produced ("Microgram" (1980), DEA, unpublished).
-
- Apparently the unusual step of open source publication was
- authorized with the knowledge that the information would reach
- clandestine chemists, and thereby avoid some potential deaths.
-
- No doubt this departure from the DEA's normal caginess must
- have sparked heated internal debate over its propriety.
-
- Speed Labs
- ----------
-
- "Polydichloric Euthimal! Those stupid bastards
- are taking Polydichloric Euthimal! It's an
- amphetamine. Strongest thing you ever saw.
- Makes you feel *wonderful*."
-
- -- Dr. Lazarus
- "Outland" (1981)
-
- The amphetamines occupy a unique position in the world of underground
- chemistry, in that they are highly marketable, profitable, as well
- as easy to make, chemically-speaking.
-
- The rise of the speed lab during the early 60s is documented in
- "Love Needs Care" (David E. Smith & John Luce. Boston: Little, Brown,
- 1970), a chronicle of the travails of the Haight-Ashbury Free Clinic
- during the 1967 Summer of Love, "The Speed Culture" (Lester Grinspoon
- & Peter Hedblom), and "Licit and Illicit Drugs" (Edward Brecher. Mt.
- Vernon, NY: Consumers Union, 1972).
-
- The first two books are out-of-print, but all three are classic works
- well worth locating for anyone interested in the sociological as well
- as the pharmacological and forensic aspects of drug use in society.
-
- The years 1979/1980 ushered in an explosion in the number of clandestine
- speed labs, and an eleven-fold increase in speed lab busts, as the DEA
- and State narcotics enforcement agencies became proficient in tracking
- them down (U.S. General Accounting Office Report GGD-82-8 (1981) and
- Frank (1983), supra).
-
- February 1980 saw the U.S. scheduling of the main clandestine precursor,
- phenyl-2-propanone (aka P-2-P). Within a few years the unregulated
- chemical l-ephedrine had replaced P-2-P as the main methamphetamine
- precursor, and was being openly advertised in drug magazines such
- as "High Times" by 1983. Since P-2-P produces the racemic mixture
- (i.e., dl-methamphetamine), and l-ephedrine the more potent d-isomer,
- this was actually a step backward, from a law enforcement and public
- health perspective.
-
- Tandem legislative efforts culminated in a 1989 Texas State Law (Texas
- Health & Safety Code 481.080 - .81) making it a felony to purchase a
- round-bottomed flask (and other glassware) without a license ("Science",
- 263:753 (1994) and "New Scientist", 941022, p. 88).
-
- As a result of the illicit manufacture of methamphetamine, which appears
- to be centered in California and Texas, and is strongly correlated with
- the Big Four bike gangs (HA's, Bandidos, Pagans, and Outlaws), who both
- finance the labs and run the distribution network, what I call the
- "Golden Age" of underground chemistry (the period of time when outlaw
- chemical and logistic skills had matured, but before law enforcement
- tactics had had time to catch up) -- the late 60s to mid 70s -- is over.
-
- [One story I've heard was an HA method from the old days in Northern
- California. A 55-gallon steel drum would be filled with a mixture of
- P-2-P, methylamine, aluminum foil, etc. The lid was quickly sealed,
- and the drum rolled into a mountain stream for cooling. On returning
- after three days, if the drum had not exploded, it would now be filled
- with raw methamphetamine ready for purification.]
-
- The Sixties bred a generation of "hippie" chemists, smugglers, and
- high-level dealers at least superficially motivated by idealism and
- the radical rejectionist politics of those turbulent times.
-
- This change in attitude was not lost on the pursuers. As one DEA
- forensic expert commented with typically dry understatement: "It
- appears that the illicit production of dangerous drugs has become
- an intellectual and professional challenge to many individuals
- associated with their misuse." (Gunn et al., "Clandestine Drug Labs",
- _J.For. Sci._ 15(1):51-64 (1970)).
-
- Changing times and the maturation of law enforcement efforts to
- counter the drug threat invariably elicited a "changing of the guard",
- as these idealists retired or were busted, and their organizations
- dismembered.
-
- In a form of negative evolution, the idealists were replaced by common
- criminals, motivated solely by opportunism, and attracted from their
- normal anti-social pursuits solely by the easy, and outrageously high
- profit margins of drug trafficking, and frequently schooled in jail by
- the imprisoned old-timers.
-
- Ironically, the problem had been metastasized by the very efforts of
- society to stamp it out.
-
- The end result was an amoral business aggressively pursued by the
- government, which could dismantle organizations like a domino game,
- rolling over one defendant after another with ruthless efficiency.
- A business riddled with informants and marked by endemic internecine
- violence, rip-offs, and government-front chemical company sting
- operations.
-
- [For a detailed and eye-opening snapshot of the "negative
- evolution" paradigm, elaborated with respect to marijuana
- cultivation in Northern California during the '80s, see
- Yves Lavigne's "Good Guy, Bad Guy: Drugs and the Changing
- Face of Organized Crime". NY: Random House (1991)]
-
- The wary should note that the mere purchase or attempted purchase of
- laboratory equipment and/or chemicals of any type can be considered
- "suspicious" unless through an established, legitimate company or
- educational institution. The take-down from time to time of labs
- run out of university Chemistry Departments -- sometimes even by
- faculty members -- testifies to the danger of this sort of shenanigan
- even with access through legitimate channels.
-
- Sorry kids, trying to buy chemicals with cash or a money order, or
- using a fake letterhead just doesn't cut it anymore. It hasn't for
- years.
-
- As a result, the manufacture of controlled substances within the U.S.
- is almost exclusively controlled by organized professional gangs
- equipped with the financial resources and sophisticated logistics
- necessary to successfully challenge the government. The days of the
- basement cowboy chemist are long gone.
-
- Between 1977 and 1984, over a dozen papers -- mostly originating
- in Europe -- appeared in the literature (_J.For.Sci._ 22:842 (1976),
- _J.For.Sci._ 22(1): 40-52 (1971), _Arch.Krim._ 162(5-6): 171-175
- (1978), _J.For.Sci._ 23(4): 693-700 (1978), _Bull. on Narc._ 36(1):
- 47-57 (1984)) on the impurities found in clandestinely-manufactured
- amphetamines.
-
- Focusing mainly on the Leuckart reaction, which is easy to find in
- the literature, and thus popular as a synthetic route, this research
- sought to "fingerprint" the output of these labs.
-
- A forensic technique first applied to illicit heroin, the idea is to
- quantitatively analyze impurities with a view to determining the
- source (ideally by batch, though in practice usually limited only to
- synthetic route or geographic locale) of the drugs.
-
- It was determined that the Leuckart reaction in particular was a
- veritable witch's brew of incomplete and side reactions, comprising
- up to 25% of the final reaction mixture: amphetamine dimers,
- pyridones, pyrimidines, pyridines, polycyclic compounds, and N-formyl
- derivatives.
-
- Unfortunately, the same legal pressure on precursors that seeks to
- root out clandestine production makes the large quantities of organic
- solvents necessary for proper purification harder and more dangerous
- to get, and forces the use of unsafe procedures, or short cuts that
- make use of the final product even more medically dangerous than it
- should be.
-
-
- LSD Manufacturing: Boys -- and Girls -- in the 'Hood
- -----------------------------------------------------
-
- "Revolution is the opium of the intellectuals."
-
- -- graffito
-
- The clandestine manufacture of LSD is logistically complex,
- requiring a variety of difficult to obtain "watched" chemicals,
- and a comparatively sophisticated lab setup. Notwithstanding
- the previous statement, like any of the illicit syntheses I
- have examined, the reaction, if done in a typical organic chem
- laboratory, would be considered routine.
-
- The LSD trade is unique within the drug world, in that those
- who are involved seem to be motivated by genuine, if misguided,
- altruism.
-
- As such, there seems to be no violence associated with any level
- of the LSD trade, and acid chemists and dealers (and many users)
- typically have a semi-mystical, proselytizing reverence for the
- substance (cf. PIHKAL). As a result, laboratory busts are rare,
- and though user demographics have changed considerably, overall
- consumption has remained more or less steady (in the tens of
- millions of hits per year), since the late Sixties.
-
- The only detailed discussion I have found on LSD pharmacology from
- an illicit chemistry perspective, is "LSD Purity",
-
- <http://www.island.org/DOCS/purity.html>
-
- an entirely speculative January 1977 "High Times" piece by Bruce
- Eisner <bruce@mindmedia.com>, whose major flaw is its lack of hard
- data.
-
- Augustus Owsley Stanley III (also known as "Owsley", aka "Owl",
- aka "Bear"; he eventually changed his name legally to "Owsley
- Stanley") was the first major "acid chemist", and he is considered
- a legendary figure from that era by some. His quite colorful
- story is chronicled in "The Electric Kool-Aid Acid Test" by Tom
- Wolfe (Bantam, 1968).
-
- Other substantial pieces on Owsley worth checking out are "The
- Creator" ("Newsweek", 680108), and, more recently, "Owsley & Me"
- ("Rolling Stone", 821125), as well as the chapter, "The Alchemist"
- in "Storming Heaven" (infra.).
-
- A recent and fairly lengthy interview with Owsley, in which he
- criticizes the accuracy of both "Storming Heaven" and the '82
- Rolling Stone piece, may be found in "Conversations with the
- Dead: the Grateful Dead Interview Book" (David Gans, N.Y.:
- Citadel Underground (1991)). This interview mostly concerns
- Owsley's musical background and association with the Grateful
- Dead as their soundman and financial patron in their early days
- in the '60s.
-
- Another Owsley interview (haven't seen this one) may be found
- in the Dead fanzine, "Dupree's Diamond News" No. 25 (August
- 1993) and No. 26.
-
- Owsley, who first burst onto the public stage when his name was
- splashed across the front-page of the "New York Times" (670628 &
- 670803), was put out of business by his December 1967 arrest at
- his suburban Orinda, California lab site with a quarter of a
- million hits of LSD and a quarter kilo of STP ("Owsley Guilty:
- 67.5 Righteous Grams", "Rolling Stone", 691115, p. 14).
-
- Owsley passed the torch to associates Nicholas Sand and Tim Scully,
- of "Orange Sunshine" [ALD-52] fame, along with the mysterious
- Ronald Stark.
-
- All three were involved with supplying psychedelics to the
- Brotherhood of Eternal Love, a loosely-based California hash
- smuggling and LSD distribution ring founded in 1966.
-
- ALD-52, 1-acetyl-LSD, was actually the first major "designer drug",
- though it being technically legal did not save Scully and Sand
- from 20 and 15 year federal prison terms respectively, in 1974.
-
- As disclosed in a 1952 U.S. Patent to Sandoz Pharmaceuticals by
- the team of Stoll, Troxler, and (Albert) Hofmann, lysergic acid
- is first converted to the diethylamide (LSD) by any of the known
- routes, and then acetylated to synthesize ALD-52:
-
- acetyl'n
- Lysergic acid --> LSD --> 1-acetyl-LSD
-
- With a published potency of 90% of LSD, but at the time completely
- legal to possess, Sand and Scully came up with the tentatively
- brilliant idea of simply reversing the reaction order in order to
- make manufacture legal as well (Tendler & May (infra); "Interview:
- Michael Kennedy" [Sand and Scully's lawyer], "High Times" (Jan.
- 1977)).
-
- By performing the acetic anhydride acetylation first, followed by
- the preparation of the diethylamide, they avoided the illegal LSD
- intermediate:
-
- acetyl'n
- Lysergic acid --> 1-acetyllysergic acid -> 1-acetyl-LSD
-
- Though such reaction flipping is in general of uncertain utility
- (it's completely reaction and reactant-dependent), in this case it
- works (cf. Johnson (1973)).
-
- And as an unpublished route, effectively Sand and Scully had come
- up with a new synthesis of ALD-52 -- which they soon put to use by
- manufacturing large amounts of it at a farmhouse lab in Windsor,
- California in 1969.
-
- Millions of "Orange Sunshine" hits later, at their 1974 trial in San
- Francisco, initially incredulous government chemists quickly recovered
- from their shock at the duo's inventiveness, by countering that even
- if they hadn't:
-
- 1) made LSD, or
- 2) made LSD at some stage in the reaction,
-
- since ALD-52 was extremely unstable to moisture, and would decompose
- to LSD soon after tableting (and, of course, on intake), they were
- still criminally liable.
-
- (Though this might seem to be paradoxical to the 90% potency claim,
- it isn't if you consider that the Molecular Weight of LSD tartrate
- divided by the M.W. of ALD-52 tartrate is about 90%.)
-
- Either way, the Judge promptly threw the book at the hapless pair.
-
- (See Burton Hersh, "The Mellon Family". N.Y.: William Morrow (1978),
- p.480-495, for a detailed account of Sand, Scully, Billy Hitchcock,
- and his Millbrook estate playground for Timothy Leary).
-
- Like many 60s counter-culture luminaries, Owsley, and later Sand,
- allied themselves with fellow outsiders the San Francisco Bay Area
- Hells Angels, providing the motorcycle gang with their start in the
- lucrative business of synthetic drug wholesaling, and ultimately
- methamphetamine manufacturing as well.
-
- The move was quite propitious for the previously aimless sociopathic
- group, motorcycle gangs being hierarchically, sociologically, and
- logistically ideal for the purpose of large scale drug trafficking.
-
- The first to recognize and exploit this possibility was George "Baby
- Huey" Wethern, Vice-President of Sonny Barger's infamous Oakland
- chapter of the HAs. Wethern turned state's evidence in 1972, and
- testified at the '74 Sand/Scully trial among others. (See the
- somewhat self-serving "A Wayward Angel", by George Wethern & Vincent
- Colnett. NY: Richard Marek (1978); see also the Michael Kennedy
- interview (supra)).
-
- I know of only two books devoted to the nether-world of illicit LSD
- manufacturing:
-
- "The Brotherhood of Eternal Love", Stewart Tendler & David May.
- London: Panther Books (1984). Out of Print. (I haven't been able
- to get my hands on anything but brief excerpts of this book [and would
- love to hear from anyone who has a copy], but see "Acid Dreams" by
- Lee & Shlain. NY: Grove Press (1985) and "Storming Heaven", by Jay
- Stevens. N.Y.: Harper & Row (1987)).
-
- (Tendler covered the "Operation Julie" bust (infra) for the
- [London Sunday] "Times", but the "Times Educational
- Supplement" (840706, p. 23) roundly criticized this book
- as a shallow, simplistic, and inadequate effort.)
-
- (See also: "The Strange Case of the Hippie Mafia", "Rolling
- Stone", 721207 & 721221 and "The Brotherhood of Eternal Love:
- The Senate Report", "High Times", Fall 1974 for opposing
- viewpoints on the scope of the Brotherhood conspiracy.)
-
- "Operation Julie", Dick Lee & Colin Pratt. London: W.H.Allen (1978).
- Out of Print. Covers the tracking and 1977 take-down of the U.K.
- organization led by Richard Kemp that formed from the regrouping of the
- post-indictment remnants of the BEL. The Kemp ring allegedly
- manufactured 60% of the world's LSD at the time, amounting to tens
- of millions of hits over a several year period.
-
- The motive of the ring's leadership was the expectation that
- widespread use of LSD by Britain's youth would catalyze leftist
- Revolution, leading to the overthrow of the aging and morally
- bankrupt _ancien regime_.
-
- For the temerity of admitting this to post-arrest police, sentences
- totaled 170 years in prison.
-
- Their bust was immortalized in the delightful electric guitar/piano
- medley, "Julie's in the Drug Squad" by the Clash (on the "Give 'em
- Enough Rope" album).
-
- (For newspaper reports on the raid and ensuing trial, see
- the [London Sunday] "Times" 770328, p. 2, and especially
- 780309, p. 1, 8 & 17.)
-
- The most recent LSD bust of note occurred in Bolinas, California in
- July 1993, and was the largest seizure of LSD in U.S. history: 1.5
- million dosage units bought over a four year period.
-
- Consistent with the unusual patterns associated with LSD trafficking,
- not only did the distribution ring consist entirely of women, including
- a grandmother in her fifties, but all refused to testify in exchange
- for reduced sentences.
-
- A Selected Bibliography on Synthetic Heroin
- -------------------------------------------
-
- "T-Bird an' Georgie let their 'gimmicks' go rotten,
- So the died of hepatitis in Upper Manhattan,
- Sly, in Vietnam -- bullet in the head,
- Bobby O.D.ed on Draino on the night that he was wed.
- They were two more friends of mine,
- Two more friends that *died*.
-
- -- "People Who Died"
- Jim Carroll Band (1980)
-
- While speed lab busts were peaking at the end of the '70s, almost
- simultaneously two entirely new and different forms of "synthetic
- heroin" (synthetic opiates, actually) began appearing commercially
- in California, making their presence felt as junkies began dropping
- like flies for unknown reasons.
-
- A major public health threat had opened simultaneously on two fronts,
- and the term "designer drug" entered the vernacular of a horrified
- public.
-
- The "original" China White fentanyl analogue was alpha-methylfentanyl,
- which the DEA initially thought was the more potent 3-methylfentanyl.
-
- Fentanyl Analogue Refs:
-
- "Chem. Eng. News" 59:71 (1981) [before they realized it was
- alpha and not 3-methyl]
-
- "Fentanyl Program", GFR1-81-4044, DEA (1981), unpublished.
-
- "Control Recommendation for a-MethylFentanyl", DEA (1981)
-
- "Federal Register" 46:46799 (1981) [Notice of Scheduling:
- Final Rule]
-
- "Anal. Chem" (Oct. 1981) "Behind the Identification of
- China White"
-
- "Science" 224:1083 (1984)
-
- "Science 85" (March 1985)
-
- Baum, "Chem. Eng. News" 63(36):7-16 (1985), excellent cover
- story on designer drugs including fentanyl & MPPP.
-
- "JAMA" 256 (22): 3061-3063 (1986); fentanyl & MPPP.
-
-
- References on the even higher potency 3-methylfentanyl, whose
- initial appearance was in Pittsburgh, and which appeared separately
- and much later, than a-methylfentanyl, and also caused some O.D.s
- (and a 45-year sentence for the chemist).
-
- 3-methyl fentanyl was also the narcotic later made by both Michael
- Hovey and George Marquardt.
-
- Monastero in "America's Habit". President's
- Commission on Organized Crime (1986)
-
- "New York Times", 881225.
-
- "Eagle", lengthy Marquardt series
-
- "Newsweek", 930621, p.32, Marquardt
-
-
- Literature cites on MPPP, of Parkinson's Disease fame:
-
- "Psych. Res." 1:249 (1979) [the original
- paper, rejected by JAMA & NEJM]
-
- "Science" 219:979 (1983)
-
- Langston, "The Sciences" 25(1):34-40 (1985)
- "The Case of the Tainted Heroin" [by the
- guy who tracked it down]
-
- "The Case of the Frozen Addict", PBS "Nova",
- (1986), transcript of show
-
- Sanford Markey, ed. "MPTP - A Neurotoxin
- Producing a Parkinsonian Syndrome" Orlando,
- Fl.: Academic Press (1986) [haven't seen
- this one; book based on Centers for Disease
- Control investigation]
-
- "The Case of the Frozen Addicts" Langston &
- Palfreman. NY: Pantheon (1995). [You've
- seen the PBS show, now read the more detailed
- book!]
-
- There are lots of other scientific papers available, but
- the above-listed are some of the main ones of interest.
-
- ------------------------------
-
- Subject: 7. "You Have Greatly Misunderstood the Purpose of the Net"
-
- "Don't get me wrong, Don Juan," I protested,
- "...but I also want to know everything I can.
- You yourself have said that knowledge is
- power."
-
- "No!" he said emphatically. "Power rests on
- the kind of knowledge one holds. What is
- the sense of knowing things that are useless?"
-
- -- "The Teachings of Don Juan:
- A Yaqui Way of Knowledge"
- Carlos Castaneda
-
- UseNet at its best is a network of some of the brightest minds in the
- civilized world, getting together to discuss whatever strikes their
- collective fancy. Professors and academics, engineers and scientists,
- polymaths, and intelligent people everywhere, getting together to kick
- ideas, information, and scurrilous personal attacks back and forth. A
- synthesis of great minds and intellects, altruistically donating their
- time and effort in glorious cosmic synergy.
-
- However, it's sad to say that, as more and more people go online, the Net
- is beginning to reflect the tawdry conglomeration that is society at large.
- One mammoth, lowest common denominator, vainglorious, pseudo-intellectual
- whore-house.
-
- To put it simply, UseNet may already have peaked.
-
- Alas.
-
- Trade Secrets, Or "Where Can I get Oil of Sassafras?", "How Do I
- ------------- Extract Codeine From Tylenol #1's?", "Can You
- Isomerize Dextromethorphan to the Narcotic Levo Form?"
-
- Just because you ask a question on the Net, does not mean
- anyone's going to answer it. Or in particular on alt.drugs --
- a newsgroup dominated by drug burn-outs, trollers, poseurs, and
- wannabes -- answer it correctly.
-
- You may get an answer to your question, but you can't
- realistically expect it when it amounts to a trade
- secret. Someone who poses such a question obviously
- has a recipe for making MDMA, aka E. The recipe requires
- oil of sassafras, or another source of safrole. Needless
- to say, the government is aware of this too, and it's
- somewhat difficult, though not impossible, to get.
-
- Broadcasting to the world, via UseNet, where to get it,
- is a good way to get the government to clamp down on
- that source of supply. Why on earth would you expect
- anyone to tell you how to get rich (illegally) anyway?
- Figure it out yourself, idiot!
-
- The codeine extraction question is another good one,
- commonly asked on alt.drugs. Tylenol #1's are OTC in
- Canada, Australia, and elsewhere. Someone was selling
- such a recipe for thousands of dollars in New Zealand a
- few years back. So why would someone give it to you
- for free? Your grasp of philanthropy is deeply flawed,
- pal.
-
- More importantly, to do that brings us the issue Number 2:
-
- Killing the Goose that Laid the Golden Egg
- ------------------------------------------
-
- I guarantee that if a simple recipe was posted for something
- such as extracting codeine from OTC medications, within
- the year, codeine would be prescription-only everywhere.
-
- But then dopers -- being the narcissistic morons that they
- are -- have never been particularly known for foresight.
-
- Ditto for isomerizing dextromethorphan, the OTC cough medicine.
- Out of chemical interest, I've wondered that myself in the past.
- But I don't know the answer, never having been interested enough
- to explore the matter.
-
- The fact of the matter, however, is that widely publicizing
- certain things -- and the Net is as wide as it gets --
- inevitably results in their negation through government
- action. I don't say this to stifle people from posting
- information, but there is such a thing as discretion, ya know.
-
- [I'm reminded of Abbie Hoffman's omission in his 1970
- classic, "Steal This Book", of the "dead baby birth
- certificate" method for obtaining false ID. Hoffman
- feared that widespread publicity would spur government
- action to close what he viewed as an escape hatch for
- fugitive radicals. Indeed, by early 1974, Hoffman was
- himself on the lam from a cocaine trafficking beef.
-
- Hoffman's self-censorship only delayed the inevitable
- however -- the scam was out only a year later in
- Frederick Forsyth's 1971 best-selling thriller, "Day
- of the Jackal", and a more detailed underground how-to
- version, "The Paper Trip" by Barry Reid (Eden Press).
-
- Interestingly, a quarter century later, this latter
- volume is still available -- along with a host of
- sequels and imitators trying to cash in on the
- corrupt and the gullible -- even though the method
- is more-or-less defunct.]
-
- Coming in a close second, are those individuals who request
- "simple high-yield recipes requiring a minimum of trouble".
- Get serious, dudes! TANSTAAFL. More importantly, why would
- anyone tell it to you for free?
-
- "Please e-mail me the Answer to my [Stupid] Question"
- ----------------------------------------------------
-
- ...Because I'm such a lazy putz that I can't be bothered to
- stick around long enough to wade through the regular traffic.
-
- Along with "tell me everything about <Insert_subject_here>"
- because you have a homework assignment due tomorrow and are
- too dumb or lazy to use the library, this probably ranks as
- one of my biggest net.peeves.
-
- "Why Didn't Anyone Answer my [Stupid] Question?"
- -----------------------------------------------
-
- No, we're not too lazy or too arrogant. Er, well, maybe we are,
- but dammit, we're not sitting here waiting around to respond to
- whatever minuscule thought percolates through your tiny, 1/4 watt
- cerebrum. That's Lamont's job.
-
- Ever hear of a library? It's an amazing place. Medicinal
- chemistry is around RM315 if you've graduated past the Dewey
- Decimal System.
-
- I started posting to the Net on the premise that I should put
- back in, for what I've gotten out of the Net. Inspired by the
- venerable Bill Nelson, who presides over in rec.pyrotechnics,
- I began posting to alt.drugs primarily safety information,
- and corrections to inaccurate posts. Other than that, if a
- post interests me, time-permitting, I *may* respond. If it
- doesn't, I don't. _C'est la vie_.
-
- You're a lot more likely to get a response if you show you've
- done your homework -- made some sort of preliminary effort to
- investigate the question yourself. I think I first got fed
- up with the intellectual parasites that infest alt.drugs (and
- much of the rest of the net) when during a lengthy thread on
- petroleum ether, some nitwit posted the very same question
- we had just finished discussing.
-
- Yes, indeed. A fool's thoughts: the briny well that never
- runs dry.
-
- Is the DEA on the Net?
- ----------------------
-
- The Internet is what the government-constructed and owned
- ARPANET has evolved into.
-
- Of course they're on the Net, fool!
-
- This was definitively confirmed in December 1994 by Lamont. No
- surprise here, except among the drug-addled.
-
- Of course, it is also the height of narcissism to think that the
- DEA gives a hoot whether you are a dope-smokin' degenerate.
- Believe me, they have more important things to worry about.
- State and local criminal investigators might, however, be a
- different matter.
-
- More importantly, the fact that you posted a message to alt.drugs
- such as, "I'm really baked!" [You're such a clever lad, aren't you?]
- may not concern you now. However you may wish to consider the fact
- that it's quite probable that someone somewhere is archiving *all*
- net traffic, and that in ten or twenty years when you do care, it
- may come back to haunt you.
-
- Such is the price of a dissipated youth.
-
- Can I Rely on Net.answers to my Questions?
- ------------------------------------------
-
- No. Next question, please.
-
- The Net is a whore that takes on all customers. This is its
- bane, as well as its beauty. The nature of alt.drugs makes
- it particularly vulnerable to inaccurate, incomplete, and
- downright erroneous answers from an assortment of flakes:
- poseurs trying to elbow their way to the front of the intell-
- ectual line, wannabe-criminals trying to attract sponsorship
- by exaggerating their expertise, and pseudo-experts trying to
- pump up their flagging egos by marking a corner of the Inner
- Circle.
-
- After all, the One-eyed Man is King in the Land of the Blind.
- Such misguided and/or maladapted individuals are most dangerous
- when they provide partially correct answers or answers lacking
- the appropriate caveats.
-
- Elevating irascibility to an art-form, I've made it a personal
- crusade to flame such net.idiots on general principles alone.
-
- On the other hand, past and present alt.drugs Hall-of-Famers such
- as J<rest of name deleted by request>, [St.] Anthony Ankrom, and
- Lamont Granquist (with an honorable mention to Steve Dyer, Eric
- Snyder, Howard Black, Pierre St. Hilaire, Malcolm, and Eli Brandt),
- can usually be counted on to provide interesting, useful, and
- accurate chemical information.
-
- Their selfless dedication to, and pursuit of the Truth is truly
- the Net at its best, and should be an inspiration to all.
-
- Unfortunately, everyone but Lamont and Steve withdrew from posting,
- or post only infrequently. Make of that what you will.
-
- But the bottom line, after all, is that you get what you pay for.
- If you rely on net.information at face value without independent
- confirmation from a reliable source, you do so at your own peril.
-
- 'Nuf said.
-
- ------------------------------
-
- Subject: 8. The Law: Do Not Pass Go, Do Not Collect $200,000
-
- "Ain't got no picture postcards,
- Ain't got no souvenirs,
- My baby, she don't know me,
- When I'm thinkin' 'bout those years."
-
- -- "New Orleans is Sinking"
- The Tragically Hip (1989)
-
- Not surprisingly, it is a serious crime everywhere to make
- and distribute drugs. Even less surprisingly, this has failed
- to make much of a dent in the manufacture and traffick in such
- substances.
-
- Since the U.S. is at the forefront of the War on Drugs, I will
- concentrate on U.S. statutes only. I no longer follow U.S.
- law particularly closely, so some of this information may be
- out of date.
-
- The U.S. Federal criminal statutes are found in the U.S.
- Code (U.S.C.), located in any North American law library.
- The USC may be found in a collection of volumes ("Titles")
- called the U.S. Code Annotated (U.S.C.A.).
-
- The drug statutes (possession, conspiracy, and sale),
- including Schedules I to V of the Controlled Substances
- Act (listing all banned and federally regulated drugs
- and precursors) are in Title 21, Sections 800-900 (21
- USC 800-900).
-
- (Interestingly, first offense drug possession is a misdemeanor
- in the U.S. under Federal law. Unfortunately, minor
- offenders are typically prosecuted under State Law, which
- usually makes drug possession a felony.)
-
- Other related Federal criminal statutes are CCE (Continuing
- Criminal Enterprise, 21 USC 848), RICO (Racketeer Influenced
- and Corrupt Organizations, 18 USC 1962), and the Controlled
- Substance Analog Enforcement Act (21 USC 802.32).
-
- RICO and CCE are the legal bludgeons the Feds use against
- drug rings that achieve any sort of success. They are
- quite draconian in both scope and harshness.
-
- State law is an entirely different and separate affair from
- Federal law and jurisdiction. Each of the fifty states has
- its own body of laws, and you can be prosecuted under _both_
- federal and state statutes, double jeopardy notwithstanding.
-
- California and Texas are two states which, in tandem with the
- level of local lab activity, have a fairly well developed
- body of statutes in this area. In particular, state precursor
- control laws preceded that of the Feds by well over a decade.
-
- For California State Law (the Health and Safety Code covers
- drug-related laws), see:
-
- <http://www.leginfo.ca.gov/calaw.html>
-
- The long-predicted (Maclean & Pournelle, unpublished (1972) &
- Brecher, supra)) rise of synthetic heroin analogues precipitated
- the passing in 1986 of the federal Controlled Substance Analogue
- Enforcement Act. This closed what had become a major loophole in
- prior legislation, the so-called "designer" drugs (pharmacologi-
- cally similar, minor chemical variants of banned drugs). Analogues,
- however, were not a recent problem. The first open source mention
- was Gunn et al. (1970, supra) (cf. Baum (1985), supra).
-
- Finally, the 1988 Chemical Diversion Trafficking Act (21 USC 802.33 -
- 802.40) placed mandatory import/export/sales reporting requirements
- on a slew of precursor chemicals.
-
- Other legal manifestations of the politics of contraband include
- laws making money-laundering (18 USC 1956, including failing to
- report large cash transactions), and the transportation of
- dangerous chemicals on airplanes Federal felonies, as well as
- civil forfeiture (21 USC 853 & 881), allowing for the summary
- confiscation of a suspected drug dealer's assets with or without
- any related criminal conviction.
-
- Income tax evasion, and using the phone (or the Net) to violate
- the drug laws are also Federal crimes.
-
- However much you think that drugs are plentiful and peachy-
- keen, you would be well-advised to note that manufacture and
- organized trafficking are not looked upon kindly. Prosecution
- is vigorous and aggressive, and these people don't fool around.
-
- Don't say you weren't warned.
-
- Additionally, the Eighth Amendment of the U.S. Bill of Rights
- was gutted by the Bail Reform Act of 1984 (upheld by the U.S.
- Supreme Court in _U.S. v. Salerno_ (1987)), to allow for pre-
- trial detention on the basis of "being a danger to the commun-
- ity", against the previous legal standard of mandatory bail
- except when there was "risk of flight".
-
- The USC is net.available:
-
- <http://www.law.cornell.edu/uscode>
- <http://www.pls.com:8001/his/usc.html>
- <http://thorplus.lib.purdue.edu/gpo/>
-
- or as gzip compressed files (by Title):
-
- <ftp://etext.archive.umich.edu/pub/Politics/Conspiracy/AJTeel/USC/>
-
- Additions to the list of contraband drugs are announced
- in the "Federal Register", a U.S. Government periodical
- found in any U.S. or Canadian law library, as well
- as any U.S. "Federal depository" public library, or
- on-line:
-
- <http://thorplus.lib.purdue.edu/gpo/>
-
- Updated schedules and ancillary drug regulations may be
- found in Title 21 of the CFR, the Code of Federal Regulations.
-
- A current list of proscribed drugs may also be obtained by writing:
-
- Drug Enforcement Administration
- Attn: Drug Control Section
- 1405 "I" Street, N.W.
- Washington, D.C. 20537
-
- ------------------------------
-
- Subject: 9. Morality & Ethics
-
- "And in between the moon and you,
- The angels get a better view,
- Of the crumbling difference,
- Between wrong and right."
-
- -- "Round Here"
- Counting Crows (1993)
-
- I've always been fascinated by the subject of outlaw chemistry.
- But radical chic aside, the more I've seen of things, the
- less and less happy I've become with the morality of it all.
-
- I've even begun to question the value of that relatively
- benign class of substances known as the psychedelics. (What
- was it that Ram Dass once said? "Psychedelics have a message
- to give, but once you get the message: hang up.")
-
- With the rest, however, -- narcotics, ups, and downs -- the
- answer is quite clear. And it ain't a good one.
-
- For no matter how delightful you find the chemistry or the
- prospect of easy money and free dope, the fact of the matter
- is that the drug business is a sordid, tawdry, and immoral one.
-
- Driven almost entirely by greed, it comes with its own grim
- toll of dead, destroyed, addicted, imprisoned, or impoverished
- humans: a constellation of suffering and misery which no
- decent man should ever want to add to.
-
- I'm not a particularly religious man, but to put it simply:
- can you imagine Jesus Christ giving his blessing to your
- crank lab?
-
- No matter how you rationalize it, there is no way to escape
- the cruel reality that drugs are about two things: money and
- power. Amassed through the corrupt exploitation of human
- weakness.
-
- And if they catch you -- and the odds are very much
- in favor of that -- you can expect no sympathy at all.
-
- Rank amateur or not, they *will* crucify your sorry ass.
-
- It's a looking glass world, with the dealers and chemists
- on one side, and an array of shameless, moral cowards:
- the demagogic Republican slime politicians, crooked and
- brutal cops, sleazy parasite lawyers, and hypocritical
- judges on the other.
-
- And they *all* profit to the detriment of society.
-
- Now, don't get me wrong: criminal sanctions against drug
- *users* are clearly not just wrong-headed, but more
- importantly, counter-productive. It is fairly obvious, as
- the Dutch and Swiss governments, and the highly respected
- "Economist" magazine see it, that drug use is a social
- problem and public health issue that should be dealt with
- as such.
-
- Unfortunately, too many have too much invested in the status
- quo.
-
- Sound public policy is built not through the cynical
- manipulations of politicians and two dollar moralists,
- but through a careful balancing of harm minimization
- to the individual, _as well as_ society at large.
-
- Until society comes to grips with that, the non-medical
- use of drugs will remain an intractable scourge that
- distorts entire economies, corrupts our institutions
- to the core, and frays the social fabric.
-
- However, the base hypocrisy of society cannot and does
- not provide moral justification for the manufacture
- and distribution of illicit drugs for personal profit.
-
- Sorry.
-
- *********************************************************
-
- "How much is enough, when your soul is empty?
- How much is enough, in the Land of Plenty?
- When you have all you want,
- And you still feel *nothing* at all,
- How much is enough?
- Is enough?"
-
- -- "How Much is Enough?"
- The Fixx (1991)
-
- *********************************************************
-
-
-